张洪波

张洪波

E-mail: hbzhang@ecust.edu.cn
职位: 硕士生导师
职称: 教授

 


个人简介:   

  张洪波 教授 毕业于华中科技大学,2000-2004年获得英国海外留学生奖学金资助(ORS)攻读英国诺丁汉特伦特大学 (Nottingham Trent University)博士学位,2004年获得博士学位。2004-2006受到英国Leverhulme Research资助分别在英国女王大学和伦敦大学作博士后研究。2006.10就职于华东理工大学致力微流体技术在生物医药中的应用研究。先后受到国家自然科学基金、上海市对外合作基金、上海市飞利浦合作基金、上海市创新行动计划等项目资助,与英国女王大学、伦敦大学及国内近10家医疗机构开展了广泛的合作。中国生物材料协会先进制造分会委员;3D打印专业委员会委员;在3D生物打印技术及微流控芯片技术方面发表50余篇SCI论文,十余项专利授权。

 

联系方法:

  梅陇路130号华东理工大学401信箱,上海 200237

  Tel: 0086-21-64253538

  Email: hbzhang@ecust.edu.cn

研究方向

   1)生物3D 打印技术

  生物3D打印构建骨、皮肤、气管组织及肿瘤模型;

  开发熔融及电纺3D打印技术


 2)微流控芯片技术 

  微纳米颗粒、肿瘤细胞分离及载药缓释微球、微泡造影剂制备

  模拟体内微环境,构建皮肤、肾器官芯片用于药物筛选;


 3)个性化可穿戴智能型外骨骼护具开发

  构建柔性欠驱动假肢、肩、肘、手可穿戴式外骨骼护具;

  姿态捕捉及生理信号结合用于步态、能耗分析及康复效果评估 

承担科研项目

  承担项目:

  1)上海市科委创新行动计划 新型抗菌水凝胶敷料的研发和临床前评价,2019.4-2022.3

  2)上海市科委“联盟计划” 3D打印活体皮肤组织块用于药物筛选研发,2016.7-2018.1

  3)国家自然科学青年基金,微气泡造影剂对癌症的基因治疗的基础研究,2008-2010;

  4)上海市科委非政府合作基金,微流体聚焦法制备治疗型微气泡造影剂的研究,2010-2012;

  5)上海市飞利浦合作基金,治疗型微气泡造影剂新型制备方法的可行性研究,2007-2009;


  企业合作项目:

  1)上海黑焰医疗科技有限公司联合研发课题,3D近电场打印机开发,2015/09-2016/08

  2)上海市肺科医院合作项目, 3D打印富含细胞生物支架用于人工气管构建,2014/12- 2016 /11

  3)黑船科技有限公司(上海)联合研发课题, 3D打印构建活体皮肤组织块及载药缓释敷料,2015/01-2018/12

  4)上海黑焰医疗科技有限公司,外骨骼康复及假肢开发,2017-1018.

获奖成果



代表性著作

  (1)P.W. Xu, F.L. Jiang, H.B. Zhang*, R.X. Yin, L. Cen and W.J. Zhang*.  Calcium Carbonate / Gelatin Methacrylate Microspheres for 3D Cell Culture in Bone Tissue Engineering Part C, 2020, 26 (8), 418-432. (IF:2.608)

  (2)S.Y. Gai, J.J. Xu, H.B. Zhang*, R.X. Yin and W.J. Zhang*. Effects of Nanofillers on the Hydrolytic Degradation of Polyesters. Tissue engineering part B, March, 5th, 2020, published online. (IF:6.512)

  (3)L. Lei, H.B. Zhang*, D. Bergstrom, T. Anthony, K.Y.Song, W.J. Zhang*. Experimental and simulation study of flow patterns in the combined flow focusing and T-junction device. Journal of Micromechanics and Microengineering, 2020, 30, 055001. (IF: 2.15)

  (4)H.P. Si, T.L. Xing, Y.L. Ding, H.B. Zhang*, R.X. Yin and W.J. Zhang. 3D Bioprinting of the Sustained Drug Release Wound Dressing with Double-Crosslinked Hyaluronic-Acid-Based Hydrogels. Polymers 2019, 11(10), 1584.(IF:3.363)

  (5)Y.H. Jia, H.B. Zhang*, S.B. Yang*, Z.H. Xi, T.T. Tang, R.X. Yin, W.J. Zhang. Electrospun PLGA membrane incorporated with Andrographolide-loaded Mesoporous Silica Nanoparticles for sustained antibacterial wound dressing. Nanomedicine, 2018, 13(22):2881-2899. (IF:5.005)

  (6)C.H. Ma, H.B. Zhang*, S. M. Yang, R. X. Yin, X. J. Yao, and W. J. Zhang. Comparison of the degradation behavior of PLGA scaffolds in micro-channel, shaking, and static conditions. Biomicrofluidics, 2018, 12, 034106.(IF:2.571)

  (7)Y. Shi, T.L. Xing, H.B. Zhang*, R.X. Yin, Sh. M. Yang, J. Wei and W.J. Zhang. Tyrosinase doped bioink for 3D bioprinting of living skin constructs. Biomedical materials, 2018, 13, 035008.(IF:2.897)

  (8)Y. Yang, L.Y. Chu, S.B. Yang, H.B. Zhang, L. Qin, O. Guillaume, D. Eglin, R. G. Richards, T.T. Tang. Dual-functional 3D-printed composite scaffold for inhibiting bacterial infection and promoting bone regeneration in infected bone defect models. Acta Biomaterialia, 2018, 79:265-275 46:112-128.(IF:6.319)

  (9)S.B. Yang, X.G. Han, Y.H. Jia, H.B. Zhang* and T.T. Tang*. Hydroxypropyltrimethyl Ammonium Chloride Chitosan Functionalized-PLGA Electrospun Fibrous Membranes as Antibacterial Wound Dressing: In Vitro and In Vivo Evaluation. Polymers 2017, 9(12), 697.(IF:3.363)

  (10)L. Lei, D. Bergstrom, B. Zhang, H.B. Zhang*, R. Yin, K.Y. Song and W.J. Zhang*. Micro/Nanospheres Generation by Fluid-Fluid Interaction Technology: A Literature Review. Recent Patents on Nanotechnology, 2017, 11, 15-33.(IF: 1.475)

  (11)R. Yin, N. Zhang, K. Wang, H. Long, T.L. Xing, J. Nie, H.B. Zhang and W.J. Zhang. Material design and photo-regulated hydrolytic degradation behavior of tissue engineering scaffolds fabricated via 3D fiber deposition. Journal of Materials Chemistry B, 2017, 5, 329-340.(IF:4.543)

  (12)Z.M. Du, N.F. Li, Y.J. Hua, Y. Shi, C.Y. Bao, H.B. Zhang, Y. Yang, Q.N. Lin, L.Y.  Zhu. Physiological pH-dependent gelation for 3D printing based on the phase separation of gelatin and oxidized dextran. Chemical Communication, 2017, 53(97):13023-13026. (IF:6.29) 

  (13)H.B. Zhang*, T.L.Xing, Y. Shi, R.X.Yin, S.M.Yang and W.J. Zhang. 3D bioprinting is not only about cell-laden structures. Chinese Journal of Traumatology, 2016, 19:187-192. (MEDLINE)

  (14)S. Duan, K. Yang, Z.H. Wang, M.T. Chen, L. Zhang*, H.B. Zhang* and C.Z. Li, Fabrication of Highly Stretchable Conductors Based on 3D Printed Porous Poly(dimethylsiloxane) and Conductive Carbon Nanotubes/Graphene Network, ACS Applied Materials & Interface, 2016, 27;8(3):2187-92.(IF:8.097)

  (15)Y. Yang, S.B. Yang, Y. Wang, Z.F. Yu, H.Y. Ao, H.B. Zhang, L. Qin, O. Guillaume, D. Eglin, R.G. Richards and T.T. Tang. Anti-infective efficacy, cytocompatibility and biocompatibility of a 3D-printed osteoconductive composite scaffold functionalized with quaternized chitosan, Acta Biomaterialia, 2016, 46:112-128.(IF:6.319)

  (16)H.B. Zhang, L. Zhou, and W.J. Zhang*. Control of Scaffold Degradation in Tissue Engineering: A Review. Tissue Engineering Part B, 2014, 10(5), 492-502.(IF:6.512)

  (17)J. Xu, Y. Xie, H.B. Zhang*, Z. Ye*, W.J. Zhang. Fabrication of PLGA/MWNTs composite electrospun fibrous scaffolds for improved myogenic differentiation of C2C12 cells. Colloids and Surfaces B: Biointerfaces, 2014, 123, 907-915.(IF:3.977)

  (18)B. Zhang, M.A.J. Moser, E.M. Zhang, Y. Luo, H.B. Zhang, W.J.  Zhang. Study of the relationship between the target tissue necrosis volume and the target tissue size in liver tumours using two-compartment finite element RFA modelling. International Journal of Hyperthermia, 2014; 30(8): 593-602. (IF:3.262)

  (19)H.B. Zhang, Y.Y. Yan, Y.Q. Zu. Numerical modelling of EHD effects on heat transfer and bubble shapes of nucleate boiling. Applied Mathematical Modeling, 2010, 34: 626-638.(IF:2.68)

  (20)J. Wei, J.F. Jia, F. Wu, S.C. Wei, H. Zhou, H.B. Zhang. Hierarchically microporous /macroporous scaffold of magnesium–calcium phosphate for bone tissue regeneration. Biomaterials, 2010, 31, 1260–1269. (IF:8.4604) 

  (21)Z. Ahmad, H.B. Zhang, U. Farook, M. Edirisinghe, E. Stride, P. Colombo. Generation of multilayered structures for biomedical applications using a novel tri-needle coaxial device and electrohydrodynamic flow.Journal of the Royal Society Interface, 2008, 5(27), 1255-1261.(IF: 3.574)

  (22)U. Farook, H.B. Zhang, M. Edirisinghe, E. Stride, N. Saffari. Preparation of microbubble suspensions by co-axial electrohydrodynamic atomization. Medical Engineering Physics. 2007, 29(7): 749-754. (IF:1.819)

  (23)H.B. Zhang and M.J. Edirisinghe. Electrospinning of Zirconia fibers from a suspension, Journal of American Ceramic Society. 2006, 89 (6): p1870-1875.(IF:2.956)

  (24)H.B. Zhang, S.N. Jayasinghe and M.J. Edirisinghe. Electrically forced microthreading of highly viscous dielectric liquids, Journal of Electrostatics, 2006, 64, p355-360.(IF:1.135)

  (25)H.B. Zhang, M.J. Edirisinghe and S.N. Jayasinghe. Flow behaviour of dielectric liquids in an electric field, Journal of Fluid Mechanics, 2006, 558: p103-111.(IF:2.821)

  (26)Q.Z. Chen, A.R. Boccaccini, H.B. Zhang, D.Z. Wang and M.J. Edirisinghe. Improved mechanical reliability of bone tissue engineering Scaffolds (zirconia) by electrospraying, Journal of American Ceramic Society, 2006, 89 (5): 1534-1539.(IF:2.841)



网页发布时间: 2019-06-03